This post is a list of the top 10 deadliest epidemics. Source: Wikipedia
- Black Death: 75 - 200 million (1346-1353)
- Spanish flu: 17 - 100 million (1918-1920)
- Plague of Justinian: 15 - 100 million (541-5449 AD)
- HIV/AIDS epidemic: 36 million (1981 - present)
- COVID-19 pandemic: 6.2 - 24 million (2019 - present)
- Third plague pandemic: 12 - 15 million (1855-1960)
- Cocoliztli epidemic: 5 - 15 million (1545-1548)
- Antonine Plague: 5 - 10 million (165-180 AD)
- Mexico smallpox epidemic: 5 - 8 million (1519-1520)
- Russia typhus epidemic: 2 - 3 million (1918-1922)